The main objective of this EPA-ESRI collaboration is to produce policy-relevant applied research at the interface between the environment, economy, and society. This report provides a summary of 12 studies, produced by the ESRI, that use a range of data and methodological approaches to provide insights into the environmental challenges facing Irish society. The studies include analyses of the impact on healthcare systems from the smoky coal ban, living in areas of higher PM2.5 levels, e-coli exceedances in drinking water and water related diseases in the summer months. It also examines the potential for a “green VAT”, the levels of emissions embedded in imports and the best ways to present information to people to enable action.